CINCINNATI, OHIO – SEPTEMBER 30: Trevor Lawrence #16 of the Jacksonville Jaguars scores a touchdown against Logan Wilson #55 of the Cincinnati Bengals during the first half of an NFL football game at Paul Brown Stadium on September 30, 2021 in Cincinnati, Ohio. (Photo by Andy Lyons/Getty Images)
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It is Week 4, and there are 12 teams on the DraftKings main slate. Within those 12 games, there are four games that potentially provide the game environment that we need to be on top of the tournament board. Then there are two games that are lower in their predictive totals but have an opportunity to be a game changer, and of course this week there is the defense you may want to prioritize.
But first, for the recap: last week the MiliMaker was taken down with an almost perfect optimized lineup. They finished with 239.80 points, with the main stack being the New York Jets versus Detroit Lions. Quarterback Geno Smith was double-stacked with his two receiving options, wide receiver Garrett Wilson and tight end Kenyon Sadiq, and the bring-back was the Lions’ running back Jahmyr Gibbs and wide receiver Jameson Williams (Williams score prevented the perfect optimization).
This week, it is time to get us on the leaderboard with the best stacks and top plays.
Best Stacks: DraftKings Main Slate
Jacksonville Jaguars @ Cincinnati Bengals -2.5, 51.5
QB Trevor Lawrence, $5,900 + RB Bhayshul Tuten, $5,600 + WR Parker Washington $6,500/ WR Ja’Marr Chase, $8,100
This lineup leaves you $4,780 for the remaining five players.
QB Joe Burrow, $6,800 + WR Ja’Marr Chase $8,100 / WR Jakobi Meyers $5,000 + WR Parker Washington $6,500
This lineup leaves you $4,720 for each of the remaining five positions.
- Last week, the Bengals allowed 127 rushing yards and an average of 7.5 yards per attempt to Pittsburgh Steelers’ running back Jaylen Warren.
- The Bengals defense has a 40% missed-tackle rate on outside runs. Tuten has forced 21 missed tackles; 15 of those have been on outside runs.
- Washington has a 30.3% target share and a 48.5% air yards share
- Meyers led the team in targets, receptions, and receiving yards last week with eight, seven, and 64, respectively.
- The Jaguars’ defense has allowed explosive pass plays at a 7.7% rate per Sharp Football Analysis. That is tied for the third most.
New England Patriots @ Buffalo Bills -7, 48.5
ORCHARD PARK, NEW YORK – JANUARY 12: James Cook #4 of the Buffalo Bills celebrates after scoring a touchdown against the Denver Broncos during the second quarter during the AFC Wild Card Playoffs at Highmark Stadium on January 12, 2025 in Orchard Park, New York. (Photo by Elsa/Getty Images)
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- The Patriots will play without cornerback Christian Gonzalez and defensive tackle Christian Barmore.
- Although the game has the second-highest predictive total, the question is where the points from the Patriots side come from. The Patriots are currently tied with the Miami Dolphins for the fewest points per game (12.0).
- The Bills lead the league in points per game, 33.7.
RB James Cook $7,400 + Buffalo Defense $3,300
This lineup leaves $5,614 for each of the remaining seven positions.
Kansas City Chiefs -5.5 @ Las Vegas Raiders, 47.5
INGLEWOOD, CALIFORNIA – NOVEMBER 30: Brock Bowers #89 of the Las Vegas Raiders catches a touchdown against Cam Hart #20 of the Los Angeles Chargers in the fourth quarter of a game at SoFi Stadium on November 30, 2025 in Inglewood, California. (Photo by Ronald Martinez/Getty Images)
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QB Kirk Cousins $5,100 + TE Brock Bowers $6,900/ RB Kenneth Walker $8,200 + Flex TE Travis Kelce $5, 000
This lineup leaves you $4,960 for each of the remaining five positions.
- Cousins has three touchdown passes in each of his last three games.
- The Raiders are allowing the third most fantasy points to the tight end position, 14.4, and have allowed five touchdowns to the position in three games.
- The Chiefs have allowed the fewest fantasy points to the quarterback position, 11.1, while giving up two touchdowns and three interceptions.
Dallas Cowboys @ Houston Texans -2.5, 47.5
HOUSTON, TEXAS – SEPTEMBER 17: Nico Collins #12 of the Houston Texans celebrates with C.J. Stroud #7 after scoring a receiving touchdown during the first quarter against the Indianapolis Colts at NRG Stadium on September 17, 2023 in Houston, Texas. (Photo by Carmen Mandato/Getty Images)
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- Cowboys’ newly acquired cornerback Joey Porter is expected to play in this game.
- Nico Collins is expected to play in this game.
- Texans’ defense is tied with the Jaguars for the most explosive pass-play rate at 7.7%.
QB CJ Stroud $5,700 + WR Nico Collins $7,200 + TE Dalton Schultz $4,800/ WR CeeDee Lamb $7,800 + George Pickens $ 6,300
This lineup leaves you $4,550 for each of the remaining four positions.
The Top Picks Option
Denver Broncos @ San Francisco 49ers -3, 46.5
The Niners are averaging the second-most points per game. Their offense is funneled through running back Christian McCaffrey, who has a 62.7% opportunity share, 21% target share, and averages 11.7 carries per game; and tight end George Kittle, who has a 19.8% target share, 29.4% red zone target share, and a 24.4% first-read target share.
SANTA CLARA, CALIFORNIA – NOVEMBER 09: George Kittle #85 of the San Francisco 49ers dives to the pylon for a touchdown during the fourth quarter of an NFL football game against the Los Angeles Rams at Levi’s Stadium on November 09, 2025 in Santa Clara, California. (Photo by Brooke Sutton/Getty Images)
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The Niners’ defense will be without Nick Bosa. Their defensive pressure rate has dropped from approximately 34% with Bosa to 17% without.
Los Angeles Chargers @ Seattle Seahawks -6.5, 43.5
This game is worth mentioning because the Chargers are currently not very good, and the Seahawks will be bouncing back from their upset loss last week to the Washington Commanders and are subjectively very good.
SEATTLE, WASHINGTON – SEPTEMBER 21: Jaxon Smith-Njigba #11 of the Seattle Seahawks scores a touchdown defended by Jonas Sanker #33 of the New Orleans Saints during the first quarter at Lumen Field on September 21, 2025 in Seattle, Washington. (Photo by Steph Chambers/Getty Images)
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Wide receiver Jaxon Smith-Njigba has a 37.9% target share and a 51.9% air yards share.
Minnesota Vikings Defense
This is Brian Flores’ revenge game against the team he is suing. He will lead his defense against a hapless Miami Dolphins team that just lost their best offensive weapon, De’Von Achane, for the season.
MINNEAPOLIS, MN. – DECEMBER 2025: Vikings Defensive Coordinator Brian Flores celebrates his defense in the first quarter as the Minnesota Vikings take on the Washington Commanders at U.S. Bank Stadium in Minneapolis, Minn., on Sunday, December 7, 2025. (Photo by Elizabeth Flores/The Minnesota Star Tribune via Getty Images)
Star Tribune via Getty Images
The Vikings’ defense has a pressure rate of 46.7% and a blitz rate of 71%.
QB Brock Purdy $6,700 + RB Christian McCaffrey $7,700 + WR Jaxon Smith-Njigba $9,100 +TE George Kittle $ 5,100 + Minnesota Defense $4, 000
This leaves you $4350 for each of the remaining four positions.
Week 4 DraftKings Main Slate
Good luck and play nice.
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